The nurse is assessing a client taking prescribed lamotrigine. Which client finding requires immediate follow-up?
The nurse is assessing a client taking prescribed lamotrigine. Which client finding requires immediate follow-up?
A. Abnormal dreams
[8%]
B. Skin blistering
[51%]
C. Dyspepsia
[18%]
D. Xerostomia
[23%]
Statistics
Subject/Lesson
Subject
Pharmacology
Lesson
Neurologic
Client Need
Test Plan
Pharmacological and Parenteral Therapies
Related Topic
Adverse Effects/Contraindications/Side Effects/Interactions
Item Type
Item Type
Analysis
Explanation
Choice B is correct. Skin blistering associated with lamotrigine therapy is a critical finding to report. This is a feature of Steven-Johnson syndrome (SJS). Lamotrigine has been implicated as causing this adverse finding.
Choices A, C, and D are incorrect. Lamotrigine may cause alteration in the mood either intentionally or unintentionally. The indication for this medication is epilepsy or bipolar disorder. Abnormal dreams are a common effect associated with this medication but are not highly concerning compared to skin blistering, which is consistent with SJS. Dyspepsia (painful digestion) and xerostomia (dry mouth) are not priority effects that should be reported as they are not life-threatening.
Additional Info
✓ Lamotrigine is a mood stabilizer and antiepileptic.
✓ This medication is indicated for bipolar disorder and epilepsy.
✓ This medication may adversely cause SJS, manifested by tender skin lesions that appear as blisters.
✓ These skin eruptions may also involve the eyes and mouth.
✓ Prompt treatment is necessary because of the risk of sepsis that may result from skin erosion.
✓ These lesions often spread fast, underlining the necessity of prompt treatment. If this should occur, the offending agent should be withdrawn.
