The nurse is caring for a client diagnosed with Reye's syndrome. Which of the following over-the-counter (OTC) medications is Reye’s syndrome associated with?
The nurse is caring for a client diagnosed with Reye's syndrome. Which of the following over-the-counter (OTC) medications is Reye’s syndrome associated with?
A. Acetaminophen
[9%]
B. Ibuprofen
[5%]
C. Aspirin
[80%]
D. Brompheniramine/pseudoephedrine
[5%]
Statistics
Subject/Lesson
Subject
Child Health
Lesson
Infectious Disease
Client Need
Test Plan
Pharmacological and Parenteral Therapies
Related Topic
Adverse Effects/Contraindications/Side Effects/Interactions
Item Type
Item Type
Knowledge/Comprehension
Explanation
Choice C is correct. Reye’s syndrome is a potentially fatal illness that can lead to liver failure and encephalopathy. Virus-infected children who are given aspirin to manage pain, fever, and inflammation are at an increased risk of developing Reye’s syndrome.
Choice A is incorrect. The use of acetaminophen has not been associated with Reye’s syndrome and can be safely given to patients with fever due to viral illnesses.
Choice B is incorrect. Ibuprofen's adverse effects include GI irritation and bleeding; in toxic doses, both renal and hepatic failure are reported. However, ibuprofen has not been associated with the onset of Reye’s disease.
Choice D is incorrect. Brompheniramine/pseudoephedrine contains a first-generation OTC antihistamine and a decongestant. Neither agent has been associated with the development of Reye’s syndrome.
Additional Info
✓ Closely monitor clients for neurological changes, such as seizures, confusion, and decreased level of consciousness, as Reye's syndrome can cause rapid neurological deterioration.
✓ Monitor ammonia levels and manage hyperammonemia with medications, such as lactulose, and other interventions, like hemodialysis, to reduce the risk of further brain damage.
✓ Administer medications, such as aspirin, carefully and with caution, as they can exacerbate Reye's syndrome.
