This nurse is caring for a client who is receiving prescribed guaifenesin. Which of the following findings would indicate a therapeutic response?
This nurse is caring for a client who is receiving prescribed guaifenesin. Which of the following findings would indicate a therapeutic response?
A. Decreased productive cough
[30%]
B. Increased mucus production
[15%]
C. Reduced mucus viscosity
[50%]
D. Less itchy, watery eyes
[5%]
Statistics
Subject/Lesson
Subject
Pharmacology
Lesson
Respiratory
Client Need
Test Plan
Pharmacological and Parenteral Therapies
Related Topic
Expected Actions/Outcomes
Item Type
Item Type
Knowledge/Comprehension
Explanation
Choice C is correct. The primary therapeutic effect of guaifenesin is to reduce mucus viscosity. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions, facilitating their removal via coughing.
Choice A is incorrect. Guaifenesin is not indicated for suppressing the cough reflex. Instead, it works by affecting mucus production. Benzonatate is an anti-tussive medication that would achieve this therapeutic effect.
Choice B is incorrect. Guaifenesin does not stimulate mucus production. It primarily works to thin and loosen mucus in the airways, making it easier to cough up.
Choice D is incorrect. Guaifenesin is not an antihistamine. It does not exert its therapeutic effects through antihistamine action. Diphenhydramine is the prototype antihistamine. Antihistamines reduce itchy, watery eyes and sneezing.
Related Videos
2 Key Topics

Expectorants
6.5 Respiratory System Drugs
Additional Info
✓ Guaifenesin works by increasing the volume and reducing the viscosity of respiratory tract secretions. It does this by stimulating the production of respiratory tract fluids, which in turn hydrates and thins the mucus, making it easier to cough up.
✓ Guaifenesin is one of the most commonly used over-the-counter medications for cough and cold symptoms in the United States.
✓ If applicable encourage the client to increase fluid intake to help loosen and thin respiratory secretions.
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