The nurse conducts a review course on older adults and medication elimination/excretion.
It would be appropriate for the nurse to note which factor may impact drug elimination? Select all that apply.
The nurse conducts a review course on older adults and medication elimination/excretion.
It would be appropriate for the nurse to note which factor may impact drug elimination? Select all that apply.
Statistics
Subject/Lesson
Subject
Pharmacology
Lesson
Medication Administration
Client Need
Test Plan
Health Promotion and Maintenance
Related Topic
Aging Process
Item Type
Item Type
Knowledge/Comprehension
Explanation
Choices A is correct. The regular physiological changes associated with the aging process that can adversely affect the excretion and elimination of drugs in the human body is the aging population's diminished glomerular filtration. This change can lead to the accumulation of medications in the body because they are not properly eliminated
Choice F is correct. As people age, several physiological changes occur. Many of these changes impact the pharmacokinetics and pharmacodynamics of medications. The regular physiological changes associated with the aging process that can adversely affect the excretion and elimination of drugs in the human body is the aging population's low-functioning nephrons. This change can lead to the accumulation of medications in the body because they are not properly eliminated.
Choice B is incorrect. Decreased hepatic enzyme functioning slows down the metabolism of medications, but not the excretion and elimination of medications in the human body.
Choice C is incorrect. Decreased peristalsis slows down the absorption of medications, but not the excretion and elimination of drugs in the human body.
Choice D is incorrect. Increased pH of the gastric secretions, rather than lower pH, slows down the absorption of medications, but not the excretion and elimination of drugs in the human body.
Choice E is incorrect. Increased alkalinity, not acidity, slows down the absorption of medications, but not the excretion and elimination of drugs in the human body.
Related Videos
3 Key Topics
Older Adult Growth and Development
14.11 Adult Growth and Development
Additional Info
✓ Older adults often have decreased renal blood flow, reduced kidney function, and decreased glomerular filtration rate, which all compound to the older adult having reduced elimination of a drug.
✓ Creatinine levels should be monitored because increased levels may suggest insult to the kidney by a nephrotoxic medication.
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