Pharmacology - Cardiovascular (24275141 (Tutorial) QID: 20181)

The nurse is preparing an educational in-service about valsartan.

Which of the following information should the nurse include?

Correct

A. “Valsartan blocks the conversion of angiotensin I to angiotensin II.”

[41%]

B. "Valsartan antagonizes angiotensin II receptors."

[39%]

C. "Valsartan stimulates alpha-2 adrenoceptors in the brainstem."

[7%]

D. "Valsartan blocks response to beta1- and beta2-adrenergic stimulation."

[13%]

Statistics

Difficulty level - Hard

39%of peers got it right

Time taken - 23 s

Subject/Lesson

• Subject

  Pharmacology

• Lesson

  Cardiovascular

Client Need

• Test Plan

  Pharmacological and Parenteral Therapies

• Related Topic

  Expected Actions/Outcomes

Item Type

• Item Type

  Knowledge/Comprehension

Explanation

Choice B is correct. Valsartan is an angiotensin-receptor blocker. The medication is prescribed for conditions such as congestive heart failure and hypertension. Valsartan antagonizes angiotensin II receptors, preventing the binding of angiotensin II to the receptors, reducing blood pressure and cardiomegaly.

Choice A is incorrect. ACE inhibitors such as enalapril prevent the conversion of angiotensin I to angiotensin II.

Choice C is incorrect. Valsartan does not stimulate alpha-2 adrenoceptors in the brainstem. Clonidine has this mechanism of action. Clonidine is another antihypertensive and is used off-label for alcohol withdrawal.

Choice D is incorrect. Beta-blockers (non-selective) block the response to beta1- and beta2-adrenergic stimulation. Non-selective beta-blockers include propranolol and labetalol.

Related Videos

2 Key Topics

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Antihypertensives & Kidneys

00:00:00

00:01:28

21.2 Renal & Blood Pressure Pharmacology

Additional Info

✓ Angiotensin renin blockers (ARBs) are a drug class comprised of medications such as losartan, valsartan, and olmesartan.

✓ ARBs are similar to ACE inhibitors in that they may cause a client to develop hyperkalemia.

✓ ARBs have a lower risk of angioedema and cough compared to ACE inhibitors.

Source : Archer Review

Last Updated - 23 Jul 2025

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